With over 35 new FDA-approved indications since the second edition—featuring groundbreaking advancements such as CAR-T therapy—this handbook serves as a quick reference for practice-changing information on complex diagnostic dilemmas, frontline treatments, refractory scenarios, and relapse management.

Purchase includes online access via most mobile devices or computers.

Key Features: New chapters on precursor states in myeloid malignancies (CHIP/CCUS), familial/inherited risks of hematologic malignancies, CAR-T versus Bispecific Treatment, and mechanisms of CAR-T resistance.

Entirely new board-style questions, enhancing critical thinking and knowledge application with every clinical chapter. Features updated chapters that concisely outline new standards of care and management considerations, accompanied by key references for further reading. Highlights essential diagnostic tools, including updated 2022 WHO and ICC classification systems, that aid in conducting critical differential diagnoses and resolving complex diagnostic dilemmas.

Delivers key updates on potential practice-changing clinical trials and paradigm-shifting treatment considerations within each disease-based chapter, ensuring clinicians stay at the forefront of hematologic oncology.

Handbook of Hematologic Malignancies – David A. MD Sallman, Ateefa MD Chaudhury, Hayder MD Saeed, Ling MD Zhang – 9780826184412

The post Handbook of Hematologic Malignancies appeared first on Le Bookshop.

We are time. We are this space, this clearing opened by the traces of memory inside the connections between our neurons. We are memory.

We are nostalgia. We are longing for a future that will not come’Time is a mystery that does not cease to puzzle us. Philosophers, artists and poets have long explored its meaning while scientists have found that its structure is different from the simple intuition we have of it.

From Boltzmann to quantum theory, from Einstein to loop quantum gravity, our understanding of time has been undergoing radical transformations. Time flows at a different speed in different places, the past and the future differ far less than we might think, and the very notion of the present evaporates in the vast universe. With his extraordinary charm and sense of wonder, bringing together science, philosophy and art, Carlo Rovelli unravels this mystery.

Enlightening and consoling. Translated by Simon Carnell and Erica Segre

The Order of Time – Carlo Rovelli – 9780141984964

The post THE ORDER OF TIME appeared first on Le Bookshop.

Discover the irresistible guide to holding more than forty critters according to advice from wildlife specialists.

Learn from the experts–a pet shop owner, a veterinarian, a wildlife photographer, and a reptile handler–how to pick up and hold dozens of species of animals, great and small, furry, scaly, and feathery, including snails, chipmunks, chickens, chinchillas, stag beetles, lizards, hamsters, owls, grasshoppers, mice, and more.

Chock full of fascinating facts, interviews with experts, and full-color photos on every page, it will delight and inform animal lovers of all stripes.

The post HOW TO HOLD ANIMALS appeared first on Le Bookshop.

In this ambitious, myth-busting book, leading scientist and internationally bestselling author Vaclav Smil investigates many of the burning questions facing the world today: Why are some of the world’s biggest food producers also the countries with the most undernourished populations?

Why is food waste a colossal 1,000kcal per person daily, and how can we solve that?

Could we all go vegan and be healthy? Should we?

How will we feed the ballooning population without killing the planet?

How Food Really Works shows how we misunderstand the essentials of where our food really comes from, how our dietary requirements shape us, and why this impacts our planet in drastic ways.

Ultimately, this data-based, rigorously researched guide explains how we will survive and thrive long into the future.

How to Feed the World – Vaclav Smil – 9780241999509

The post HOW TO FEED THE WORLD appeared first on Le Bookshop.

Jenara Nerenberg was shocked to discover that her “symptoms”–only ever labeled as anxiety– were considered autistic and ADHD. Being a journalist, she dove into the research and uncovered neurodiversity.

A framework that moves away from pathologizing “abnormal” versus “normal” brains and instead recognizes the vast diversity of our mental makeups. When it comes to women, sensory processing differences are often overlooked, masked, or mistaken for something else entirely.

Nerenberg explores these topics in depth, delving into:

• Flawed systems that focus on diagnosing younger, male populations.
• How people assigned female at birth are conditioned to blend in and conform to gender expectations.
• How women often don’t learn about their neurological differences until they are adults, if at all.
• The impact of millions living with undiagnosed or misdiagnosed neurodivergences
• How the misidentification leads to depression, anxiety, low self-esteem, and shame.

Practical solutions for neurodivergent people to thrive, not just survive.

Divergent Mind is the much-needed answer for women who have a deep sense that they are “different.” Sharing real stories from women with high sensitivity, ADHD, autism, misophonia, dyslexia, SPD, and more, Nerenberg explores how these brain variances present differently in women. And dispels widely-held misconceptions.

Nerenberg offers us a path forward, describing changes in how we communicate, how we design our surroundings, and how we can better support divergent minds.

When we allow our wide variety of brain makeups to flourish, we create a better tomorrow for us all.

Divergent Mind : Thriving in a World That Wasn’t Designed for You – Jenara Nerenberg – 9780062876805

The post DIVERGENT MIND : THRIVING IN A WORLD THAT WASN’T DESIGNED FOR YOU appeared first on Le Bookshop.

‘Mindblowing’ Michael Pollan.

Why do we know so much more about the cosmos than our own consciousness? Are there limits to the scientific method? Why do we assume that only science, mathematics and technology reveal truth?

The Flip shows us what happens when we realise that consciousness is fundamental to the cosmos and not some random evolutionary accident or surface cognitive illusion; that everything is alive, connected, and ‘one’. We meet the people who have made this visionary, intuitive leap towards new forms of knowledge: Mark Twain’s prophetic dreams, Marie Curie’s séances, Einstein’s cosmically attuned mind. But these forms of knowledge are not archaic; indeed, they are essential in a universe that has evolved specifically to be understandable by the consciousnesses we inhabit.

The Flip peels back the layers of our beliefs about the world to reveal a visionary, new way of understanding ourselves and everything around us, with huge repercussions for how we live our lives. After all, once we have flipped, we understand that the cosmos is not just human. The human is also cosmic.

THE FLIP – Jeffrey J. Kripal – 15.90 € – 9780141992563

The post THE FLIP : WHO YOU REALLY ARE AND WHY IT MATTERS appeared first on Le Bookshop.

We know the causes of death and disease among women all over the world. Governments and philanthropists have funded plenty of initiatives over recent decades. So why isn’t it working?

Across the globe, women’s health is being caught in the crossfires of politics: from the repeal of abortion rights and the bombing of Ukrainian maternity hospitals, to the exploitation of vulnerable patients and women health workers.

In this powerful and moving exploration, Professor Sophie Harman offers smart solutions on how to fix this devastating crisis.

Sick of It : The Global Fight for Women’s Health – Sophie Harman – 9780349017242

The post SICK OF IT : THE GLOBAL FIGHT FOR WOMEN’S HEALTH appeared first on Le Bookshop.

Almost every aspect of life takes the form of a cycle, whether it be the change of the seasons or the phases of the moon. Cycles both big and small affect us all, and so when we can become more aware and in tune with them – when we flow – we can achieve more ease and empowerment in everyday life. This book is your guide to uniting 4 sacred cycles: lunar, menstrual, seasonal and life.

Discover hundreds of practical ideas and tips to harnessing the wisdom of the cycles, including:Food medicineSex tipsHormonal skin healthExercise and training tipsSleep pattern informationRelationship adviceExercises, meditations and spellsSeasonal ritualsIntention-settingCrystal and chakra healing and moreBy the end, you will not only be comforted with a toolbox of cyclical strategies to optimize your everyday life but feel utterly worthy without patriarchal approval. Deepen your intuition and honour your body through full awareness of how your cycles, within and without, affect your mood, body and soul.

The post FLOW appeared first on Le Bookshop.

How did wet nurses drive civilization? Are women always the weaker sex? Is sexism useful for evolution? And are our bodies at war with our babies?

In Eve, Cat Bohannon answers questions scientists should have been addressing for decades. With boundless curiosity and sharp wit, she covers the past 200 million years to explain the specific science behind the development of the female sex. Eve is not only a sweeping revision of human history, it’s an urgent and necessary corrective for a world that has focused primarily on the male body for far too long.

Bohannon’s findings, including everything from the way C-sections in the industrialized world are rearranging women’s pelvic shape to the surprising similarities between pus and breast milk, will completely change what you think you know about evolution and why Homo sapiens have become such a successful and dominant species, from tool use to city building to the development of language.

Eve : How The Female Body Drove 200 Million Years of Human Evolution – Cat Bohannon – 9781529156171 – 18.50€

The post EVE : HOW THE FEMALE BODY DROVE 200 MILLION YEARS OF HUMAN EVOLUTION appeared first on Le Bookshop.

We may imagine that science is a process of breakthroughs and light bulb moments. But in reality, science goes wrong 99% of the time. Almost every idea a scientist comes up with is quickly disproved by a failed experiment or rival research.

Science moves at a rate of inches per decade and we often like it that way. But occasionally, just occasionally, a complete fluke happens and changes everything as we know it. From an untimely sneeze in a petri dish leading to the groundbreaking creation of antibiotics, to the incredible discovery of microwaves via melted chocolate, Accidental is a rip-roaring adventure through science gone wrong, and accidentally changing humanity for the better.

Accidental: The Greatest Unintentional Scientific Breakthroughs & How They Changed the World – Tim James – 9781472148421

The post ACCIDENTAL: THE GREATEST UNINTENTIONAL SCIENTIFIC BREAKTHROUGHS appeared first on Le Bookshop.